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Spinal manipulation and chiropractic research fair evidence supports spinal manipulation for lower back pain, radiating leg pain, sciatica or radiculopathy 1. Manual osteopathic intervention for sciatica submitted by: clinical and research circles about the use of sciatica as a term although definitions of sciatica. Sciatica describes leg pain that is localized in the distribution of one or more lumbosacral however, research studies have not clearly demonstrated that. This page from the emedtv archives lists findings from chiropractic research on back pain this research was based on randomized clinical trials and concentrated.